Accès gratuit
Numéro
Biologie Aujourd'hui
Volume 207, Numéro 1, 2013
Page(s) 39 - 54
DOI https://doi.org/10.1051/jbio/2013006
Publié en ligne 23 mai 2013
  • Bakkour N., Lin Y.-L., Maire S., Ayadi L., Mahuteau-Betzer F., Nguyen C.-H., Mettling C., Portales P., Grierson D., Chabot B., Jeanteur P., Branlant C., Cordeau P., Tazi J., Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance. PloS Pathogens, 2007, 3, 1530–1539. [CrossRef] [PubMed] [Google Scholar]
  • Bauvois B., Puiffe M.-L., Bongui J.-B., Paillat S., Monneret C., Dauzonne D., Synthesis and biological evaluation of novel flavone-8-acetic acid derivatives as reversible inhibitors of aminopeptidase N/CD13. J Med Chem, 2003, 46, 3900–3913. [CrossRef] [PubMed] [Google Scholar]
  • Blackwell H.E., Zhao Y., Chemical genetic approaches to plant biology. Plant Physiology, 2003, 133, 448–455. [CrossRef] [PubMed] [Google Scholar]
  • Blondel M., Couplan E., Di Rago J.-P., Dauzonne D., Palladino M., Celotto A., Compounds for the treatment of mitochondrial diseases, European Patent, 2009, EP N° 10719072.0. [Google Scholar]
  • Ceccaldi A., Rajavelu A., Champion C., Rampon C., Jurkowska R.A., Jankevicius G., Namaud-Beaufort C.S., Ponger L., Gagey N., Dali Ali H., Tost J., Vriz S., Ros S., Dauzonne D., Jeltsch A., Guianvarc’h D., B., Arimondo P., C5-DNA Methyltransferase inhibitors: from screening to effects on Zebrafish embryo development, Chembiochem, 2011, 12, 1337–1345. [CrossRef] [PubMed] [Google Scholar]
  • Ceccaldi A., Rajavelu A., Ragozin S., Sénamaud-Beaufort C., Bashtrykov P., Testa N., Dali-Ali, H., Maulay-Bailly C., Amand S., Guianvarc’h D, Jeltsch A., Arimondo P., Identification of Novel Inhibitors of DNA methylation by Screening of a Chemical Library, ACS Chem Biol, 2013, 8, 543–548. [CrossRef] [PubMed] [Google Scholar]
  • Chong C.R., Sullivan D.J. Jr., New uses for old drugs. Nature, 2007, 448, 645–646. [CrossRef] [PubMed] [Google Scholar]
  • Cochet C., Expanding the chemical diversity of CK2 inhibitors. Mol Cell Biochem, 2008, 316, 71–85. [CrossRef] [PubMed] [Google Scholar]
  • Cornelius J.Connor O., Henning W., Beckmannw S., David G., Spring R., Diversity-oriented synthesis: producing chemical tools for dissecting biology. Chem Soc Rev, 2012, 41, 4444–4456. [CrossRef] [PubMed] [Google Scholar]
  • Dömling A., Small molecular weight protein-protein interaction antagonists an insurmountable challenge. Curr Opin Chem Biol, 2008, 12, 281–291. [CrossRef] [PubMed] [Google Scholar]
  • Ekins S., Mestres J., Testa B., In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling. Br J Pharmacol, 2007, 152, 9–20. [CrossRef] [PubMed] [Google Scholar]
  • Erve A., Saoudi Y., Thirot S., Landras C., Florent J.-C., Nguyen C.-H., Grierson D., Popov A., Bena435, a new cell-permeant photoactivated green fluorescent DNA probe. Nucleic Acids Res, 2006, 34, e43. [CrossRef] [PubMed] [Google Scholar]
  • Garcia-Serna, R., Mestres J., Chemical probes for biological systems. Drug Discov Today, 2011, 16, 99–105. [CrossRef] [PubMed] [Google Scholar]
  • Hergenrother P.J., Obtaining and screening compound collections: a user’s guide and a call to chemists. Curr Opin Chem Biol, 2006, 10, 213–218. [CrossRef] [PubMed] [Google Scholar]
  • Hoang T.M.N., Favier B., Valette A., Barette C., Nguyen C.H., Lafanéchère L., Grierson D.S., Dimitrov S., Molla A., Benzo[e]pyridoindoles, novel inhibitors of the Aurora kinases. Cell Cycle, 2009, 8, 765–772. [CrossRef] [PubMed] [Google Scholar]
  • Ho C.H., Piotrowski J., Dixon S.J., Baryshnikova A., Costanzo M., Boone C., Combining functional genomics and chemical biology to identify targets of bioactive compounds. Curr Opin Chem Biol, 2011, 15, 66–78. [CrossRef] [PubMed] [Google Scholar]
  • Keriel A., Mahuteau-Betzer F., Jacquet C., Plays M., Grierson D., Sitbon M., Tazi J., Protection against Retrovirus Pathogenesis by SR Protein Inhibitors. PlosOne, 2009, 4, e4533. [Google Scholar]
  • Kugawa F., Watanabe M., Tamanoi F., Chemical Biology/Chemical Genetics/Chemical Genomics: Importance of Chemical Library. Chem-Bio Inf J, 2007, 3, 49–68. [Google Scholar]
  • Le L.T.T., Vu H.L., Nguyen C.H., Molla A., Basal Aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase. Biology Open, 2013, 8, 289–296. [Google Scholar]
  • Lachance H., Wetzel S., Kumar K., Waldmann H., Charting, navigating, and populating natural product chemical space for drug discovery. J Med Chem, 2012, 55, 5989 − 6001. [CrossRef] [PubMed] [Google Scholar]
  • Lopez-Ramos L.M., Prudent R., Moucadel V., Sautel C.F., Barette C., Lafanéchère L., Mouawad L., Grierson D., Schmidt F., Florent J.-C., Filippakopoulos P., Bullock A.N., Knapp S., Reiser J.-B., Cochet C., New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights. FASEB J, 2010, 24, 3171–3185. [CrossRef] [PubMed] [Google Scholar]
  • Maréchal E., Roy S., Lafanéchère L., Chémogénomique, des petites molécules pour explorer le vivant, EDP Sciences, Collection Grenoble Sciences, 2007, 258 p. [Google Scholar]
  • McCarthy A., The NIH Molecular Libraries Program: Identifying Chemical Probes for New Medicines. Chem Biol, 2010, 17, 549–550. [CrossRef] [PubMed] [Google Scholar]
  • Newman D.J., Cragg G.M., Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010. J Nat Prod, 2012, 75, 311 − 335. [Google Scholar]
  • NhungHoang T.M., Favier B., Valette A., Barette C., Nguyen C.-H., Lafanéchère L., Grierson D.S., Dimitrov S., Molla A., Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases. Cell Cycle, 2009, 5, 765–772. [Google Scholar]
  • Popov A., Juhem A., Florent J.-C., Nguyen C.H., Utilisation de quinolones pour la préparation de médicaments, nouvelles quinolones et leur procédé de synthèse. French patent FR 10/00829, 01/03/2010 [Google Scholar]
  • Prudent R., Moucadel V., Lopez Ramos M., Aci S., Laudet B., Mouawad L., Barette C., Einhorn J., Einhorn C., Denis J.-N., Bisson G., Schmidt F., Roy S., Lafanéchère L., Florent J.C., Cochet, Expending the chemical diversity of CK2 inhibitors. Mol Cell Biochem, 2008a, 316, 71–85. [CrossRef] [PubMed] [Google Scholar]
  • Prudent R., Lopez-Ramos M., Moucadel V., Barette C., Grierson D., Mouawad L., Florent J.-C., Lafanéchère L., Schmidt F., Cochet C., Salicylaldehyde derivatives as new protein kinase CK2 inhibitors. Biochem Biophys Acta, 2008b, 1780, 1412–1420. [CrossRef] [Google Scholar]
  • Prudent R., Moucadel V., Nguyen C.-H., Barette C., Schmidt F., Florent J.-C., Lafanéchère L., Sautel C.F., Duchemin-Pelletier E., Spreux E., Filhol O., Reiser J.-B., Cochet C., Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2. Cancer Res, 2010, 70, 9865–9874. [CrossRef] [PubMed] [Google Scholar]
  • Prudent R., Vassal-Stermann E., Nguyen C.-H., Pillet C., Martinez A., Prunier C., Barette C., Soleilhac E., Filhol O., Beghin A., Valdameri G., Honoré S., Aci-Sèche S., Grierson D., Antonipillai J., Li R., Di Pietro A., Dumontet C., Braguer D., Florent J.-C., Knapp S., Bernard O., Lafanéchère L., Pharmacological inhibition of LIM Kinase stabilizes microtubules and inhibits neoplastic growth. Cancer Res, 2012, 17, 4429–4439. [CrossRef] [PubMed] [Google Scholar]
  • Schreiber S., Small molecules: The missing link in the central dogma. Nature Chem Biol, 2005, 2, 64–66. [CrossRef] [Google Scholar]
  • Spring D.R., Chemical genetics to chemical genomics: small molecules offer big insights. Chem Soc Rev, 2005, 34, 472–482 [CrossRef] [PubMed] [Google Scholar]
  • Stockwell B.R., Exploring biology with small organic molecules. Nature, 2004, 432, 846–854. [CrossRef] [PubMed] [Google Scholar]
  • Vassal E., Barette C., Fonrose X., Dupont R., Sans-Soleilhac E., Lafanéchère L., Miniaturization and validation of a sensitive multi-parametric cell-based assay for the concomitant detection of microtubule-destabilizing and microtubule-stabilizing agents. J Biomol Screen, 2006, 11, 377–389. [CrossRef] [PubMed] [Google Scholar]
  • Varin T., Schuffenhauer A., Ertl P., Renner S., Mining for bioactive scaffolds with scaffold networks: Improved compound set enrichment from primary screening data. J Chem Inf Model, 2011, 51, 1528–1538. [CrossRef] [PubMed] [Google Scholar]
  • Vidalain P.-O., Lucas-Hourani M., Tangy F., Munier-Lehmann H., Dauzonne D., Nouveaux dérivés utiles en tant qu’agents antiviraux. European Patent, 2012, EP2420495 A1. [Google Scholar]
  • Wang Y., Bolton E., Dracheva S., Karapetyan K., Shoemaker B.A., Suzek T.O., Wang J., Xiao J., Zhang J., Bryant S.H., An overview of the PubChem BioAssay resource. Nucleic Acids Res, 2010, 38, 255 − 266. [CrossRef] [Google Scholar]
  • Wang Y., Xiao J., Suzek T.O., Zhang J., Wang J., Zhou Z., Han L., Karapetyan K., Dracheva S., Shoemaker B.A., Bolton E., Gindulyte A., Bryant S.H., PubChem’s BioAssay Database. Nucleic Acids Res, 2012, 40, Database issue (D1): D400-D412 doi: 10.1093/nar/gkr1132 [Google Scholar]
  • Wetzel S., Bon R.S., Kumar K., Waldmann H., Biology-Oriented Synthesis. Angew Chem Int Ed Engl, 2011, 50, 10800–10826. [CrossRef] [PubMed] [Google Scholar]

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