Accès gratuit
Biologie Aujourd'hui
Volume 210, Numéro 1, 2016
Page(s) 19 - 26
Section Cellules pluripotentes induites : de la modélisation des maladies à la thérapie cellulaire (Journée Claude Bernard 2015)
Publié en ligne 10 juin 2016
  • Abifadel, M., Varret, M., Rabès, J.-P., Allard, D., Ouguerram, K., Devillers, M., Cruaud, C., Benjannet, S., Wickham, L., Erlich, D., Derré, A., Villéger, L., Farnier, M., Beucler, I., Bruckert, E., Chambaz, J., Chanu, B., Lecerf, J.M., Luc, G., Moulin, P., Weissenbach, J., Prat, A., Krempf, M., Junien, C., Seidah, N.G., and Boileau, C. (2003). Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet, 34, 154-156. [CrossRef] [PubMed] [Google Scholar]
  • Alagille, D., Estrada, A., Hadchouel, M., Gautier, M., Odièvre, M., and Dommergues, J.P. (1987). Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia) : review of 80 cases. J Pediatr, 110, 195-200. [CrossRef] [PubMed] [Google Scholar]
  • Alpini, G., Ulrich, C., Roberts, S., Phillips, J.O., Ueno, Y., Podila, P.V., Colegio, O., LeSage, G.D., Miller, L.J., and LaRusso, N.F. (1997). Molecular and functional heterogeneity of cholangiocytes from rat liver after bile duct ligation. Am J Physiol, 272, G289-G297. [PubMed] [Google Scholar]
  • Alpini, G., Ueno, Y., Glaser, S.S., Marzioni, M., Phinizy, J.L., Francis, H., and Lesage, G. (2001). Bile acid feeding increased proliferative activity and apical bile acid transporter expression in both small and large rat cholangiocytes. Hepatol, 34, 868-876. [CrossRef] [Google Scholar]
  • Alvaro, D., Metalli, V.D., Alpini, G., Onori, P., Franchitto, A., Barbaro, B., Glaser, S.S., Francis, H., Cantafora, A., Blotta, I., Attili, A.F., and Gaudio, E. (2005). The intrahepatic biliary epithelium is a target of the growth hormone/insulin-like growth factor 1 axis. J Hepatol, 43, 875-883. [CrossRef] [PubMed] [Google Scholar]
  • Alvaro, D., Macarri, G., Mancino, M.G., Marzioni, M., Bragazzi, M., Onori, P., Corradini, S.G., Invernizzi, P., Franchitto, A., Attili, A.F., Gaudio, E., and Benedetti, A. (2007). Serum and biliary insulin-like growth factor I and vascular endothelial growth factor in determining the cause of obstructive cholestasis. Ann Intern Med, 147, 451-459. [CrossRef] [PubMed] [Google Scholar]
  • Baiocchi, L., LeSage, G., Glaser, S., and Alpini, G. (1999). Regulation of cholangiocyte bile secretion. J Hepatol, 31, 179-191. [CrossRef] [MathSciNet] [PubMed] [Google Scholar]
  • Benedetti, A., Bassotti, C., Rapino, K., Marucci, L., and Jézéquel, A.M. (1996). A morphometric study of the epithelium lining the rat intrahepatic biliary tree. J Hepatol, 24, 335-342. [CrossRef] [PubMed] [Google Scholar]
  • Brown, M.S., Goldstein, J.L. (1986). A receptor-mediated pathway for cholesterol homeostasis. Science, 232, 34-47. [CrossRef] [PubMed] [Google Scholar]
  • Cayo, M.A., Cai, J., DeLaForest, A., Noto, F.K., Nagaoka, M., Clark, B.S., Collery, R.F., Si-Tayeb, K., and Duncan, S.A. (2012). JD induced pluripotent stem cell-derived hepatocytes faithfully recapitulate the pathophysiology of familial hypercholesterolemia. Hepatol, 56, 2163-2171. [CrossRef] [Google Scholar]
  • Chen, C.-P. (2007). Meckel syndrome : genetics, perinatal findings, and differential diagnosis. Taiwan J Obstet Gynecol, 46, 9-14. [CrossRef] [PubMed] [Google Scholar]
  • Davila, S., Furu, L., Gharavi, A.G., Tian, X., Onoe, T., Qian, Q., Li, A., Cai, Y., Kamath, P.S., King, B.F., Azurmendi, P.J., Tahvanainen, P., Kääriäinen, H., Höckerstedt, K., Devuyst, O., Pirson, Y., Martin, R.S., Lifton, R.P., Tahvanainen, E., Torres, V.E., and Somlo, S. (2004). Mutations in SEC63 cause autosomal dominant polycystic liver disease. Nat Genet, 36, 575-577. [CrossRef] [PubMed] [Google Scholar]
  • De Assuncao, T.M., Sun, Y., Jalan-Sakrikar, N., Drinane, M.C., Huang, B.Q., Li, Y., Davila, J.I., Wang, R., O’Hara, S.P., Lomberk, G.A., Urrutia, R.A., Ikeda, Y., Huebert, R.C. (2015). Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes. Lab Invest, 95, 684-696. [CrossRef] [PubMed] [Google Scholar]
  • Dianat, N., Dubois-Pot-Schneider, H., Steichen, C., Desterke, C., Leclerc, P., Raveux, A., Combettes, L., Weber, A., Corlu, A., and Dubart-Kupperschmitt, A. (2014). Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells. Hepatology, 60, 700-714. [CrossRef] [MathSciNet] [PubMed] [Google Scholar]
  • Drenth, J.P.H., te Morsche, R.H.M., Smink, R., Bonifacino, J.S., and Jansen, J.B.M.J. (2003). Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease. Nat Genet, 33, 345-347. [CrossRef] [PubMed] [Google Scholar]
  • Dru di Metalli, V., Mancino, M.G., Mancino, A., Torrice, A., Gatto, M., Attili, A.F., Alpini, G., and Alvaro, D. (2007). Bile salts regulate proliferation and apoptosis of liver cells by modulating the IGF1 system. Dig Liver Dis, 39, 654-662. [CrossRef] [PubMed] [Google Scholar]
  • Fattahi, F., Asgari, S., Pournasr, B., Seifinejad, A., Totonchi, M., Taei, A., Aghdami, N., Salekdeh, G.H., and Baharvand, H. (2012). Disease-Corrected Hepatocyte-Like Cells from Familial Hypercholesterolemia-Induced Pluripotent Stem Cells. Mol Biotechnol, 54, 863-873. [CrossRef] [Google Scholar]
  • Fedeles, S.V., Tian, X., Gallagher, A.-R., Mitobe, M., Nishio, S., Lee, S.H., Cai, Y., Geng, L., Crews, C.M., and Somlo, S. (2011). A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nat Genet, 43, 639-647. [CrossRef] [PubMed] [Google Scholar]
  • Fiorotto, R., Scirpo, R., Trauner, M., Fabris, L., Hoque, R., Spirli, C., and Strazzabosco, M. (2011). Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice. Gastroenterology, 141, 1498-1508. [CrossRef] [PubMed] [Google Scholar]
  • Francis, H.L., DeMorrow, S., Franchitto, A., Venter, J.K., Mancinelli, R.A., White, M.A., Meng, F., Ueno, Y., Carpino, G., Renzi, A., Baker, K.K., Shine, H.E., Francis, T.C., Gaudio, E., Alpini, G.D., and Onori, P. (2011). Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms. Lab Invest, 92, 282-294. [CrossRef] [MathSciNet] [PubMed] [Google Scholar]
  • Garcia, C.K., Wilund, K., Arca, M., Zuliani, G., Fellin, R., Maioli, M., Calandra, S., Bertolini, S., Cossu, F., Grishin, N., Barnes, R., Cohen, J.C., and Hobbs, H.H. (2001). Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein. Science, 292, 1394-1398. [CrossRef] [PubMed] [Google Scholar]
  • Ghodsizadeh, A., Taei, A., Totonchi, M., Seifinejad, A., Gourabi, H., Pournasr, B., Aghdami, N., Malekzadeh, R., Almadani, N., Salekdeh, G.H., and Baharvand, H. (2010). Generation of liver disease-specific induced pluripotent stem cells along with efficient differentiation to functional hepatocyte-like cells. Stem Cell Rev, 6, 622-632. [CrossRef] [PubMed] [Google Scholar]
  • Goldstein, J.L., Brown, M.S. (2009). The LDL Receptor. Arterioscler Thromb Vasc Biol, 29, 431-438. [CrossRef] [PubMed] [Google Scholar]
  • Goldstein J.L., Hobbs H.H., and Brown M.S. (2001) Familial hypercholesterolemia. In: The Metabolic and Molecular Bases of Inherited Disease, Scriver C.S. et al., eds., McGraw-Hill Book Co, New-York, edn 8, pp. 2863-2913. [Google Scholar]
  • Hofmann, J.J., Zovein, A.C., Koh, H., Radtke, F., Weinmaster, G., and Iruela-Arispe, M.L. (2010). Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development : insights into Alagille syndrome. Development, 137, 4061-4072. [CrossRef] [PubMed] [Google Scholar]
  • Innerarity, T.L., Weisgraber, K.H., Arnold, K.S., Mahley, R.W., Krauss, R.M., Vega, G.L., and Grundy, S.M. (1987). Familial defective apolipoprotein B-100 : low density lipoproteins with abnormal receptor binding. Proc Natl Acad Sci USA, 84, 6919-6923. [CrossRef] [Google Scholar]
  • Kanno, N., LeSage, G., Glaser, S., Alvaro, D., and Alpini, G. (2000). Functional heterogeneity of the intrahepatic biliary epithelium. Hepatol, 31, 555-561. [CrossRef] [MathSciNet] [Google Scholar]
  • Khachadurian, A.K. (1964). The inheritance of essential familial hyper-cholesterolemia. Am J Med, 37, 402-407. [CrossRef] [PubMed] [Google Scholar]
  • Khachadurian, A.K. (1988). Clinical features, diagnosis and frequency of familial hypercholesterolemia. Beitr Zur Infusionstherapie Contrib Infus Ther, 23, 26-32. [Google Scholar]
  • Lahuna, O., Rastegar, M., Maiter, D., Thissen, J.P., Lemaigre, F.P., and Rousseau, G.G. (2000). Involvement of STAT5 (signal transducer and activator of transcription 5) and HNF-4 (hepatocyte nuclear factor 4) in the transcriptional control of the hnf6 gene by growth hormone. Mol Endocrinol, 14, 285-294. [CrossRef] [PubMed] [Google Scholar]
  • Lecchi, S., Fabris, L., Spirli, C., Cadamuro, M., Fiorotto, R., and Strazzabosco, M. (2010). Cholangiocyte Biology as Relevant to Cystic Liver Diseases. In : K.F. Murray, and A.M. Larson (eds). Fibrocystic Diseases of the Liver, Humana Press, Totowa, N.J., pp. 23-43. [Google Scholar]
  • Leung, A., Nah, S.K., Reid, W., Ebata, A., Koch, C.M., Monti, S., Genereux, J.C., Wiseman, R.L., Wolozin, B., Connors, L.H., Berk, J.L., Seldin, D.C., Mostoslavsky, G., Kotton, D.N., and Murphy, G.J. (2013). Induced Pluripotent Stem Cell Modeling of Multisystemic, Hereditary Transthyretin Amyloidosis. Stem Cell Rep, 1, 451-463. [CrossRef] [Google Scholar]
  • Li, Z., White, P., Tuteja, G., Rubins, N., Sackett, S., and Kaestner, K.H. (2009). Foxa1 and Foxa2 regulate bile duct development in mice. J Clin Invest, 119, 1537-1545. [CrossRef] [PubMed] [Google Scholar]
  • Liu, Z., Sakamoto, T., Ezure, T., Yokomuro, S., Murase, N., Michalopoulos, G., and Demetris, A.J. (1998). Interleukin-6, hepatocyte growth factor, and their receptors in biliary epithelial cells during a type I ductular reaction in mice : interactions between the periductal inflammatory and stromal cells and the biliary epithelium. Hepatol, 28, 1260-1268. [CrossRef] [Google Scholar]
  • Maetzel, D., Sarkar, S., Wang, H., Abi-Mosleh, L., Xu, P., Cheng, A.W., Gao, Q., Mitalipova, M., and Jaenisch, R. (2014). Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells. Stem Cell Rep, 2, 866-880. [CrossRef] [Google Scholar]
  • Mohamadnejad, M., Pournasr, B., Bagheri, M., Aghdami, N., Shahsavani, M., Hosseini, L.A., Taghiabadi, E., Azizi, H., Heidari, I., Akhlaghpoor, S., Calandra, S., Malekzadeh, R., and Baharvand, H. (2010). Transplantation of allogeneic bone marrow mesenchymal stromal cell-derived hepatocyte-like cells in homozygous familial hypercholesterolemia. Cytotherapy, 12, 566-568. [CrossRef] [PubMed] [Google Scholar]
  • Ogawa, M., Ogawa, S., Bear, C.E., Ahmadi, S., Chin, S., Li, B., Grompe, M., Keller, G., Kamath, B.M., and Ghanekar, A. (2015). Directed differentiation of cholangiocytes from human pluripotent stem cells. Nat Biotechnol, 33, 853-861. [CrossRef] [PubMed] [Google Scholar]
  • Okada, K., Shimizu, Y., Nambu, S., Higuchi, K., and Watanabe, A. (1994). Interleukin-6 functions as an autocrine growth factor in a cholangiocarcinoma cell line. J Gastroenterol Hepatol, 9, 462-467. [CrossRef] [PubMed] [Google Scholar]
  • Rashid, S.T., Corbineau, S., Hannan, N., Marciniak, S.J., Miranda, E., Alexander, G., Huang-Doran, I., Griffin, J., Ahrlund-Richter, L., Skepper, J., Semple, R., Weber, A., Lomas, D.A, and Vallier, L. (2010). Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. J Clin Invest, 120, 3127-3136. [CrossRef] [PubMed] [Google Scholar]
  • Rastegar, M., Rousseau, G.G., and Lemaigre, F.P. (2000). CCAAT/enhancer-binding protein-alpha is a component of the growth hormone-regulated network of liver transcription factors. Endocrinology, 141, 1686-1692. [PubMed] [Google Scholar]
  • Sampaziotis, F., Cardoso de Brito, M., Madrigal, P., Bertero, A., Saeb-Parsy, K., Soares, F.A.C., Schrumpf, E., Melum, E., Karlsen, T.H., Bradley, J.A., Gelson, W.T., Davies, S., Baker, A., Kaser, A., Alexander, G.J., Hannan, N.R., and Vallier, L. (2015). Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation. Nat Biotechnol, 33, 845-852. [CrossRef] [PubMed] [Google Scholar]
  • Simard, M., Manthos, H., Giaid, A., Lefèbvre, Y., and Goodyer, C.G. (1996). Ontogeny of growth hormone receptors in human tissues : an immunohistochemical study. J Clin Endocrinol Metab, 81, 3097-3102. [PubMed] [Google Scholar]
  • Si-Tayeb, K., Idriss, S., Champon, B., Caillaud, A., Pichelin, M., Arnaud, L., Lemarchand, P., May, C.L., Zibara, K., and Cariou, B. (2016). Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia. Dis Model Mech, 9, 81-90. [PubMed] [Google Scholar]
  • Strazzabosco, M., Fabris, L. (2012). Development of the bile ducts : Essentials for the clinical hepatologist. J Hepatol, 56, 1159-1170. [CrossRef] [PubMed] [Google Scholar]
  • Strazzabosco, M., Fabris, L., and Spirlì, C. (2005). Pathophysiology of cholangiopathies. J Clin Gastroenterol, 39, S90-S102. [CrossRef] [PubMed] [Google Scholar]
  • Strick-Marchand, H. (2004). Bipotential mouse embryonic liver stem cell lines contribute to liver regeneration and differentiate as bile ducts and hepatocytes. Proc Natl Acad Sci USA, 101, 8360-8365. [CrossRef] [Google Scholar]
  • Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. (2007). Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors. Cell, 131, 861-872. [CrossRef] [PubMed] [Google Scholar]
  • Tanimizu, N. (2004). Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors. J Cell Sci, 117, 3165-3174. [CrossRef] [PubMed] [Google Scholar]
  • Tanimizu, N., Miyajima, A., and Mostov, K.E. (2007). Liver Progenitor Cells Develop Cholangiocyte-Type Epithelial Polarity in Three-dimensional Culture. Mol Biol Cell, 18, 1472-1479. [CrossRef] [PubMed] [Google Scholar]
  • Wang, P., Cong, M., Liu, T.-H., Yang, A.-T., Cong, R., Wu, P., Tang, S.-Z., Xu, Y., Wang, H., Wang, B.-E., Jia, J.D., and You, H. (2010). Primary isolated hepatic oval cells maintain progenitor cell phenotypes after two-year prolonged cultivation. J Hepatol, 53, 863-871. [CrossRef] [PubMed] [Google Scholar]
  • Yokomuro, S., Tsuji, H., Lunz, J.G., Sakamoto, T., Ezure, T., Murase, N., Demetris, A.J. (2000a). Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factorβ1, and Activin A: Comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells. Hepatology, 32, 26-35. [CrossRef] [PubMed] [Google Scholar]
  • Yokomuro, S., Lunz, J.G., 3rd, Sakamoto, T., Ezure, T., Murase, N., Demetris, A.J. (2000b). The effect of interleukin-6 (IL-6)/gp130 signalling on biliary epithelial cell growth, in vitro. Cytokine, 12, 727-730. [CrossRef] [PubMed] [Google Scholar]
  • Yu, B., He, Z.-Y., You, P., Han, Q.-W., Xiang, D., Chen, F., Wang, M.-J., Liu, C.-C., Lin, X.-W., Borjigin, U., Zi, X.Y., Li, J.X., Zhu, H.Y., Li, W.L., Han, C.S., Wangensteen, K.J., Shi, Y., Hui, L.J., Wang, X., and Hu, Y.P. (2013). Reprogramming fibroblasts into bipotential hepatic stem cells by defined factors. Cell Stem Cell, 13, 328-340. [CrossRef] [Google Scholar]
  • Yu, J., Vodyanik, M.A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J.L., Tian, S., Nie, J., Jonsdottir, G.A., Ruotti, V., Stewart, R., Slukvin, I.I., and Thomson, J.A. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science, 318, 1917-1920. [CrossRef] [PubMed] [Google Scholar]
  • Zhao, D., Chen, S., Cai, J., Guo, Y., Song, Z., Che, J., Liu, C., Wu, C., Ding, M., and Deng, H. (2009). Derivation and Characterization of Hepatic Progenitor Cells from Human Embryonic Stem Cells. PLoS One, 4, e6468. [CrossRef] [PubMed] [Google Scholar]
  • Zhang, S., Chen, S., Li, W., Guo, X., Zhao, P., Xu, J., Chen, Y., Pan, Q., Liu, X., Zychlinski, D., et al. (2011). Rescue of ATP7B function in hepatocyte-like cells from Wilson’s disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin. Hum. Mol. Genet., 20, 3176-3187. [CrossRef] [PubMed] [Google Scholar]

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